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目的比较比索洛尔、美托洛尔分别联合胺碘酮治疗频发室性早搏的临床效果。方法 120例频发室性早搏患者,按照随机数字表法分为对照组及治疗组,各60例。对照组采用美托洛尔联合胺碘酮治疗,治疗组采用比索洛尔联合胺碘酮治疗。比较两组临床疗效及频发室性早搏数量改善情况。结果治疗前,两组患者早搏数量比较,差异无统计学意义(P>0.05);治疗后,两组患者早搏数量均较本组治疗前降低,且治疗组低于对照组,差异均具有统计学意义(P<0.05)。治疗组治疗总有效率为91.7%,高于对照组的76.7%,差异具有统计学意义(P<0.05)。结论比索洛尔、美托洛尔联合胺碘酮治疗频发室性早搏均具有较好的临床效果,但比索洛尔的优势更为明显,且可显著减少室性早搏数量,临床可将其作为首选方法全面推广普及。
Objective To compare the clinical effects of bisoprolol and metoprolol combined with amiodarone in the treatment of frequent ventricular premature beats. Methods A total of 120 patients with frequent premature ventricular contractions were divided into control group and treatment group according to random number table method, 60 cases each. The control group was treated with metoprolol combined with amiodarone, and the treatment group was treated with bisoprolol combined with amiodarone. The clinical efficacy and frequency of premature ventricular contractions were compared between the two groups. Results Before treatment, there was no significant difference in the number of premature beats between the two groups (P> 0.05). After treatment, the number of premature beats in both groups was lower than before treatment, and the treatment group was lower than the control group, with statistical differences Significance (P <0.05). The total effective rate of treatment group was 91.7%, higher than 76.7% of control group, the difference was statistically significant (P <0.05). Conclusion Bisoprolol and metoprolol combined with amiodarone in the treatment of frequent ventricular premature beats have a good clinical effect, but the advantage of bisoprolol is more obvious, and can significantly reduce the number of premature ventricular contractions, clinically its As the preferred method to promote universal access.