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目的:探讨腰硬联合麻醉分娩镇痛(combined spinal-epidural analgesia,CSEA)对妊娠期糖尿病(gestationaldiabetes mellitus,GDM)母儿血糖的影响。方法:回顾选择2013年6月-2014年6月期间苏州市立医院母子中心确诊GDM产妇65例,且均是平产分娩者,其中使用CSEA的33例为研究组;不使用CSEA的32例为对照组。结果:CSEA后1小时末梢血糖值比较,研究组明显低于对照组(P<0.05);分娩后两组孕妇血糖水平比较,研究组明显低于对照组(P<0.05)。研究组新生儿足跟血测定血糖明显高于对照组(P<0.05)。结论:腰硬联合麻醉分娩镇痛可能可以减轻GDM产妇在分娩过程中内分泌的改变,能有效改善母儿血糖。
Objective: To investigate the effect of combined spinal-epidural analgesia (CSEA) on blood glucose in gestational diabetes mellitus (GDM). Methods: From June 2013 to June 2014, 65 patients with confirmed GDM in the mother-child center of Suzhou Municipal Hospital were retrospectively selected. All of them were delivered by labor. Among them, 33 were treated with CSEA, and 32 without CSEA were Control group. Results: Compared with the control group (P <0.05), the blood glucose level of the study group was significantly lower than that of the control group (P <0.05). The neonatal heel blood test in the study group was significantly higher than that in the control group (P <0.05). Conclusion: Combined spinal and epidural anesthesia for labor analgesia may reduce the endocrine changes of GDM maternal during childbirth, and can effectively improve maternal blood sugar.