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作者用14只开胸犬,观察急性心肌缺血早期降低血液粘度对心脏收缩功能的改善效应。结果:(1)阻断冠脉40mm时,测得STI和血液动力学各指标发生明显变化。PEP延长,LVET缩短,PEP/LVET比值增大,动脉收缩压升高以及心输出量减少,各参数与对照值间有显著性差异;(2)阻断冠脉10min后行右旋糖酐等速,等量血流稀释,基本
The authors used 14 thoracotomy dogs to observe the effect of reducing blood viscosity on cardiac systolic function in early stage of acute myocardial ischemia. Results: (1) Significant changes of STI and hemodynamics were detected when the coronary artery was blocked at 40mm. PEP prolonged, LVET shortened, PEP / LVET ratio increased, arterial systolic blood pressure increased and cardiac output decreased, the parameters were significantly different from the control value; (2) 10min after blocking the coronary artery dextran constant velocity, etc. Dilution of blood flow, basic