β_2-激动剂是目前最有效的支气管扩张剂,也是世界上使用最广泛的哮喘治疗药,其吸入剂使用20多年来,使成百万患者的症状得以缓解。但令人奇怪的是最近10年来哮喘的发病率和死亡率反而升高了。统计学证明,这种倾向与β_2-激动剂的用量上升是平行的。根据Saskatchewan等7年间药物治疗的计算机记录统计进行的流行病学研究,证明使用大剂量β_2-激动剂的病人死亡和濒死的危险明显增加,但在有些国家中并未见到这种增加。由 Beta 2-agonists are currently the most effective bronchodilators and are the most widely used asthma medication in the world. Their inhalants have been used for more than two decades to relieve the symptoms of millions of patients. However, it is strange that the incidence and mortality of asthma have actually risen in the past 10 years. Statistics show that this tendency is in parallel with the increase in the amount of β 2 -agonists. Epidemiological studies based on computerized statistics of drug treatment for seven years, such as Saskatchewan, have shown a significant increase in the risk of dying and dying in patients using high-dose beta 2-agonists, although this increase has not been observed in some countries. by