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目的 microRNAs是一类非编码蛋白的小RNA分子,通过与靶基因mRNA 3’端的非编码区(3’UTRS)结合而在转录后水平调控基因表达,调节细胞增殖、分化、代谢、凋亡、器官发育等生物学过程。肝脏有很强的再生能力,是研究再生的重要材料。因此,我们在文中总结了microRNAs对肝再生调节作用的研究进展。
The purpose of microRNAs is a class of small non-coding small RNA molecules that regulate gene expression at the post-transcriptional level by binding to the 3’UTR of the 3’end of the target gene mRNA and thereby regulating cell proliferation, differentiation, metabolism, apoptosis, Organ development and other biological processes. Liver has a strong ability to regenerate, is an important material for research regeneration. Therefore, we summarize the research progress of the regulation of microRNAs on liver regeneration.