Hamburg(1972)曾描述1例罕见的伴有前房积脓继而穿孔的角膜溃疡。他将眼前部炎症组织中发现的囊性小体,归类为“未知的微生物”。由棘阿米巴(Acanthamoeba)引起的第1例眼部感染,是1973年在华盛顿举行的一次军事病理研究所会议上报告的。此后,在1975年的奥斯陆欧洲14届眼病理协会年会和60届牛津眼科大会上,由Norman Ashton和Jones等将棘阿米巴引起的眼部感染症状正式记录在各种文献上。尔后,人们才逐渐认识了棘阿米巴眼病。 Hamburg (1972) described one case of a rare corneal ulcer accompanied by empyema and perforation. He classified cystic bodies found in the frontal inflammatory tissue as “unknown microorganisms.” The first case of ocular infection caused by Acanthamoeba was reported at a conference of the Military Pathology Institute in Washington in 1973. Since then, at the Oslo Congress of Europe in Europe at the Fourth Eye Association 1975 and at the 60th Oxford Ophthalmology Congress, Norman Ashton and Jones et al. Documented the ocular infection symptoms caused by Acanthamoeba in various sources. Later, people began to recognize the eye of Acanthamoeba.