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对河南省某化工厂三硝基甲苯(TNT)作业现场劳动卫生学调查结果发现,车间空气中TNT浓度多数超过国家最高容许浓度(MAC=1mg/m3),TNT作业工人皮肤污染严重。血清铁测定结果表明,TNT接触组与HBsAg阳性组极显著高于对照组(P<00005),HBsAg阳性组显著高于TNT接触组(P<00025)。推测TNT与HBV诱发的肝损害部分机理可能与机体处于氧化应激状态有关。
The survey of labor hygiene of TNT in a chemical plant in Henan Province found that the TNT concentration in the air of the workshop mostly exceeded the national maximum allowable concentration (MAC = 1 mg / m3), and the TNT workers had serious skin pollution. Serum iron assay results showed that TNT exposure group and HBsAg positive group was significantly higher than the control group (P <00005), HBsAg positive group was significantly higher than TNT exposure group (P <00025). It is speculated that part of the mechanism of liver damage induced by TNT and HBV may be related to the body in the state of oxidative stress.