宿主对疟原虫的免疫应答中,细胞外的裂殖子可能是重要的靶子。作者用代谢标记法,研究了恶性疟原虫裂殖子蛋白质和糖蛋白的组分、合成及其抗原性。作者选用取自夜猴的恶性疟原虫(K~+株分离物FVO),经山梨醇同步培养,用Percoll梯度离心法,由上而下可得到疟原虫的滋养体、裂殖体、环状体小团及没有感染的红细胞。收集滋养体和裂殖体,去除环状体和大 Among host immune responses to Plasmodium, extracellular merozoites may be important targets. The authors used the metabolic labeling method to study the composition, synthesis and antigenicity of Plasmodium falciparum merozoite proteins and glycoproteins. The authors used P. falciparum (K + strain isolate FVO) obtained from the cynomolgus monkey and cultured synchronously with sorbitol using a gradient centrifugation method with Percoll to obtain trophozoites, schizonts, Small groups and no infected red blood cells. Collect trophozoites and schizonts, remove rings and large