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目的：探讨急性缺血性脑血管病后神经机能失联络现象及其临床意义。方法：采用９９ｍＴｃ－ＥＣＤ－ＳＰＥＣＴ技术，动态观测３６例急性单侧基底节梗塞患者脑血流的变化，同时评估患者的神经系统体征及脑梗塞的体积。结果：在发病３．４ｄ内，１１例（约３１％）患者出现了不同程度的神经机能失联络，表现为梗塞灶对侧小脑（８例）、同侧顶区（２例）和同侧枕区（１例）的血流量减少。此１１例患者脑梗塞体积明显大于２５例无神经机能失联络现象者（Ｐ＜０．０５）。两组病人入院时神经功能缺损积分相近，但前者３周后的积分明显大于后者。结论：急性脑梗塞后神经机能失联络的出现可能是神经系统功能预后不良的一个指标。
Objective: To investigate the neurological dysfunction after acute ischemic cerebrovascular disease and its clinical significance. Methods: The changes of cerebral blood flow in 36 patients with acute unilateral basal ganglia infarction were observed dynamically by 99mTc-ECD-SPECT. The signs of the nervous system and the volume of cerebral infarction were also evaluated. Results: Within 3.4 days of onset, 11 cases (about 31%) had different degrees of neurological loss, showing the contralateral cerebellum (8 cases), the ipsilateral apical region (2 cases) and the ipsilateral Occipital area (1 case) decreased blood flow. The infarct volume in 11 patients was significantly greater than that in 25 patients without neurological loss (P <0.05). Two groups of patients admitted to neurological deficit points similar, but the former 3 weeks after the score was significantly greater than the latter. CONCLUSION: The appearance of neurological derangement after acute cerebral infarction may be an indicator of the poor prognosis of nervous system function.