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为了解癫痫持续状态后发展为癫痫的病人的海马体积变化,作者对一例全身性强直一阵挛性癫痫持续状态后发展成为慢性癫痫的病人进行了MRI观察。 患者为女性,30岁。1991年9月因低热一周引起全身性癫痫持续状态(SE)。SE发作后2天检查示:脑脊液(CSF)淋巴细胞增多,达72个/μl;血糖正常;抗HSV1克隆带存在。血清HSV1抗体滴度在病后3～4周,从20上升至160。胸片、脑部CT、DSA以及肌肉活检均正常。SE持续的2周时间内应用静脉注射硫喷妥钠等治疗。病后2个月,患者的神经系统开始康复,但出现记忆力缺失,并出现继发性全身性抽搐后反复癫痫发作,形成难治性癫痫。当病变从额叶延伸至颞叶前部时,与其表现出的“抽搐症状”相符合,有迹象表明此时患者处于
To understand the changes in hippocampal volume in patients with epilepsy following status epilepticus, the authors performed MRIs on a patient with chronic epilepsy who developed persistent tetanic and clonic status epilepticus. Patient is female, 30 years old. September 1991 caused by a week of low-grade status epilepticus (SE). Two days after the onset of SE, the examination showed that CSF increased lymphocytes to 72 cells / μl, blood glucose was normal, and anti-HSV1 cloning band existed. Serum HSV1 antibody titers in the disease after 3 to 4 weeks, from 20 to 160. Chest radiographs, brain CT, DSA, and muscle biopsies were all normal. SE for 2 weeks continuous application of intravenous therapy such as thiopental. Two months after the illness, the patient’s nervous system began to recover, but the memory loss, and repeated seizures after repeated seizures, the formation of intractable epilepsy. When the lesion extends from the frontal lobe to the front of the temporal lobe, it is consistent with the “convulsive symptom” it exhibits, and there are indications that the patient is at this time