本文报告1例有家族史的不安腿综合征(RLS),并对其家系进行调查分析。 1 病例资料先证者,女性,41岁,干部。22年前无明确诱因开始出现双侧小腿深部异常不适,以酸胀、痛为主,时有麻痛、烧灼感、蚁走感,难以忍受,按压揉搓、活动均使症状缓解。过度劳累,精神刺激均可使症状加重、发作频繁。白天坐久时即发作,须站立活动才能缓解,夜间 This article reports one case of restless leg syndrome (RLS) with a family history and conducts a survey of its pedigree. 1 case information proband, female, 41 years old, cadres. 22 years ago, there is no clear incentive to begin to appear deep bilateral lower extremity discomfort, soreness, pain-based, when a numb, burning sensation, ants feel unbearable, press rubbing, activities are relieved symptoms. Over-exertion, mental stimulation can make the symptoms worse, seizures frequent. When sedentary during the day when the attack, to stand activity can ease, night