目的　评价长期服用小剂量阿司匹林对急性缺血性脑血管病严重程度的影响。方法　将 32 1例急性缺血性脑血管病患者根据发病前是否服用阿司匹林进行随机分组和病例配对研究 ,临床评分作为病情严重程度的指标。结果　随机分组和病例配对中 ,服药组临床评分为 17 39± 9 90 ,未服药组为 16 2 2± 9 98,两组比较 ,差异无显著意义。结论　长期服用小剂量阿司匹林不能降低急性缺血性脑血管病的严重程度 Objective To evaluate the long-term use of low-dose aspirin on the severity of acute ischemic cerebrovascular disease. Methods A total of 321 patients with acute ischemic cerebrovascular disease were randomized and matched according to whether aspirin was taken before the onset of disease or not. The clinical score was used as an indicator of the severity of the disease. Results In the randomized and case-matched groups, the clinical score of the medication group was 17 39 ± 9 90 and that of the non-medication group was 16 2 2 ± 988. There was no significant difference between the two groups. Conclusion Long-term use of low-dose aspirin can not reduce the severity of acute ischemic cerebrovascular disease