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手性药物的研究与开发已成为当今世界新药发展的战略方向和热点领域。1999年,全球手性药物市场销售额第一次超过1000亿美元,达到1150亿美元,比。1998年增长16％,占世界药品市场总销售额3600亿美元的32％。预计2003年将达到1460亿美元,以8％的速度增长。通过外消旋转化、上市药物组合物和开发新型手性单一异构体药物,手性药物正在成为制药公司谋求利益和提升地位的工具。手性中间体、对映选择技术和手性分离技术为精细化学品工业提供了机会。
The research and development of chiral drugs have become the strategic direction and hotspot of the development of new drugs in the world today. In 1999, the global sales of chiral drugs surpassed 100 billion U.S. dollars for the first time, reaching 115 billion U.S. dollars. An increase of 16% in 1998 and accounting for 32% of the total global pharmaceutical sales of 360 billion U.S. dollars. Expected in 2003 will reach 146 billion US dollars, an increase of 8%. Chiral drugs are emerging as a tool for pharmaceutical companies seeking profit and advancement through racemic conversion, marketed pharmaceutical compositions and the development of new chiral monoisomer drugs. Chiral intermediates, enantioselective techniques and chiral separation techniques provide an opportunity for the fine chemicals industry.