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乙型肝炎患者体内的病毒清除依赖于机体针对病毒的特异性T细胞应答[1-2]。乙型肝炎病毒(hepatitis B virus,HBV)特异性细胞毒性T淋巴细胞(cytotoxic T lymphocyte,CTL)识别MHC-Ⅰ类分子与细胞内合成的病毒蛋白肽复合物,抗原递呈细胞是HBV感染细胞或被病毒感染后凋亡的细胞。CTL
Virus clearance in patients with hepatitis B depends on the body’s specific T cell response to the virus [1-2]. Hepatitis B virus (HBV) -specific cytotoxic T lymphocytes (CTLs) recognize MHC class I molecules and intracellular synthetic viral protein peptide complexes. The antigen-presenting cells are HBV-infected cells Or cells that are apoptotic after infection with the virus. CTL