Fault diagnosis and monitoring are very important for complex chemical process. There are numerous methods that have been studied in this field, in which the effective visualization method is still challenging. In order to get a better visualization effect, a novel fault diagnosis method which combines self-organizing map (SOM) with Fisher discriminant analysis (FDA) is proposed. FDA can reduce the dimension of the data in terms of maximizing the separability of the classes. After feature extraction by FDA, SOM can distinguish the different states on the output map clearly and it can also be employed to monitor abnormal states. Tennessee Eastman (TE) process is employed to illustrate the fault diagnosis and monitoring performance of the proposed method. The result shows that the SOM integrated with FDA method is efficient and capable for real-time monitoring and fault diagnosis in complex chemical process. There are numerous methods that have been studied in this field, in which the effective visualization method is still challenging. In order to get a better visualization effect, a novel fault diagnosis method which combines The FDA can reduce the dimension of the data in terms of maximizing the separability of the classes. After feature extraction by FDA, SOM can distinguish the different states on the output map clearly and it can also be employed monitor abnormal states. Tennessee Eastman (TE) process is employed to illustrate the fault diagnosis and monitoring performance of the proposed method. The result shows that the SOM integrated with FDA method is efficient and capable for real -time monitoring and fault diagnosis in complex chemical process.