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目的:探讨影响大面积脑梗死患者预后的临床因素。方法:收集在我院住院治疗的86例经CT或MRI证实的大面积脑梗死患者的临床资料,根据随访结果是否存活,分为死亡组和幸存组,进行影响两组预后结果的各项因素单因素分析后,将有统计学意义的因素进入Logistic回归模型进行多因素分析。结果:单因素分析结果:死亡组的年龄(≥60岁)、梗死面积(≥200 cm3)、意识障碍、完全瘫痪、合并症、CT检查有脑水肿症、CT检查有出血症与幸存组患者的差异均具有统计学意义(P<0.05);多因素分析结果:年龄≥60岁(OR=2.860,95%CI=1.841~17.931)、梗死面积≥200 cm3(OR=3.524,95%CI=1.841~17.931)、有合并症(OR=1.882,95%CI=1.275~5.464)、CT检查有出血症(OR=5.662,95%CI=2.862~8.677)是影响大面积梗死患者预后的主要危险因素(P<0.05)。结论:年龄≥60岁、梗死面积≥200 cm3、有合并症、CT检查有出血症是影响大面积梗死患者预后的主要危险因素。
Objective: To explore the clinical factors affecting the prognosis of patients with large area cerebral infarction. Methods: The clinical data of 86 patients with large-area cerebral infarction confirmed by CT or MRI in our hospital were collected and divided into death group and survivor group according to whether the follow-up result survived. The factors influencing prognosis of the two groups After univariate analysis, statistically significant factors were entered into Logistic regression model for multivariate analysis. Results: The results of univariate analysis showed that the age of the deceased group (≥60 years old), the infarct size (≥200 cm3), unconsciousness, complete paralysis, comorbidities, cerebral edema in CT examination, CT in patients with hemorrhagic disease and survivors (OR = 2.860, 95% CI = 1.841-17.931), infarct size ≥200 cm3 (OR = 3.524, 95% CI = 1.841 ~ 17.931). Complications (OR = 1.882, 95% CI = 1.275-5.464) were the main risk factors for the prognosis of large infarcts in patients with CT. Factor (P <0.05). Conclusion: The age ≥ 60 years old, infarction area ≥ 200 cm3, with complications, CT examination of hemorrhagic disease is a major risk factor affecting the prognosis of large infarction patients.