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目的 评价区域灌注化疗对胰腺癌的效果并探讨相关并发症的防治。方法 对 36例不能切除的胰腺癌行选择性动脉插管 ,并予 5 氟脲嘧啶、阿霉素、顺铂 (5 Fu、ADM、DDP)行区域灌注化疗。结果 31例患者接受 6 5周期化疗 ,完全缓解 6例 ,部分缓解 15例 ,行胰十二指肠二步切除 1例。平均生存 9.3± 4.2个月 ,发生各类并发症 14例 ,死亡 2例。结论 胰腺癌区域灌注化疗可改善患者生活质量 ,延长患者生存期 ,但也应重视并发症的防治。
Objective To evaluate the effect of regional infusion chemotherapy on pancreatic cancer and explore the prevention and treatment of related complications. Methods Thirty-six patients with unresectable pancreatic cancer were treated with selective arterial intubation, and 5 fluorouracil, doxorubicin, and cisplatin (5 Fu, ADM, DDP) were given for regional infusion chemotherapy. RESULTS: Thirty-one patients received 65 cycles of chemotherapy, 6 had complete remission, 15 had partial remission, and 1 had double pancreaticoduodenectomy. The average survival time was 9.3±4.2 months. There were 14 cases of various complications and 2 deaths. Conclusion Regional infusion chemotherapy for pancreatic cancer can improve the quality of life of patients and prolong the survival of patients, but it should also pay attention to the prevention and treatment of complications.