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目的探讨缓解期慢性阻塞性肺疾病(COPD)家庭长期氧疗的临床作用。方法选择36例缓解期COPD患者,随机分为治疗组(18例)、对照组(18例),两组均给予常规抗炎、解痉平喘,祛痰止咳等治疗,治疗组在此基础上给予鼻导管吸氧1~2 L/min,至少15 h/d,总疗程6个月,定期随访患者。结果治疗后治疗组低氧血症显著改善(P<0.01),红细胞压积显著下降(P<0.01),但肺功能变化不明显(P>0.05),最大运动能力及精神状态较前明显改善。结论缓解期COPD家庭长期氧疗提高患者生活质量具有重大意义,值得临床推广。
Objective To investigate the clinical effect of long-term oxygen therapy in chronic obstructive pulmonary disease (COPD) Methods Thirty-six patients with COPD were randomly divided into treatment group (18 cases) and control group (18 cases). Both groups were given conventional anti-inflammatory, antispasmodic and antiasthmatic drugs, expectorant and cough treatment. The treatment group was given on this basis Nasal catheter oxygen 1 ~ 2 L / min, at least 15 h / d, the total course of 6 months, regular follow-up of patients. Results After treatment, the hypoxemia in treatment group was significantly improved (P <0.01), hematocrit decreased significantly (P <0.01), but lung function did not change significantly (P> 0.05), and maximal exercise capacity and mental status were significantly improved . Conclusion COPD long-term oxygen therapy in remission patients improve the quality of life of great significance, worthy of clinical promotion.