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对正常不吸烟者45例、无症状吸烟者44例、慢支20例、轻度肺气肿34例、中重度肺气肿23例进行最大呼气肺功能测定。结果显示,正常不吸烟组和无症状吸烟组之间FEF_(25-75％)差异显著(P<0.05),V_(50)差异非常显著(P<0.01);无症状吸烟者的异常检出率分别为22.7％和20.5％,表明可作为检出小气道早期病变的指标。三组慢阻肺病人之间FEV_1％和V_(75)的差异均有非常显著意义(P<0.01);异常检出率随病情演变而递增,提示对慢阻肺病变程度的判断有一定价值。
45 cases of normal non-smokers, asymptomatic smokers in 44 cases, 20 cases of chronic bronchitis, mild emphysema in 34 cases, 23 cases of moderate and severe emphysema, the maximum expiratory lung function test. The results showed that the difference of F_ (25-75%) between normal non-smoking group and asymptomatic smoking group was significant (P <0.05) and V_ (50) was significant (P <0.01) Rates were 22.7% and 20.5%, respectively, indicating that it can be used as an indicator of early detection of small airways. The differences of FEV_1% and V_ (75) between the three groups of COPD patients were significant (P <0.01). The abnormal detection rate increased with the progression of the disease, suggesting a certain value for judging the extent of COPD .