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目的:探讨甲氨蝶呤与米非司酮联合应用在异位妊娠治疗中的临床效果。方法:将80例异位妊娠患者按照治疗方案随机分为观察组与对照组各40例,观察组给予甲氨蝶呤+米非司酮治疗,对照组仅给予甲氨蝶呤治疗,比较两组治疗有效率及不良反应发生情况。结果:观察组治疗总有效率(97.5%)显著高于对照组(72.5%)(P<0.01),两组不良反应发生率无显著差异(P>0.05)。结论:甲氨蝶呤联合米非司酮用于异位妊娠的保守治疗,疗效肯定,安全可靠。
Objective: To investigate the clinical effect of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods: Eighty patients with ectopic pregnancy were randomly divided into observation group (40 cases) and control group (40 cases). Methotrexate and mifepristone were given respectively in the observation group and methotrexate alone in the control group Group treatment efficiency and adverse reactions occurred. Results: The total effective rate (97.5%) in the observation group was significantly higher than that in the control group (72.5%) (P <0.01). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion: Methotrexate combined with mifepristone for the conservative treatment of ectopic pregnancy, positive effect, safe and reliable.