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含氟有机化合物由于其独特性,在医药、农药、材料等与人口健康、国民生活和国防建设紧密相关的领域中具有重要的应用.虽然在过去的几年中向有机分子中引氟取得了很大发展,但是发展温和条件下,高效实用,具有普适性的引氟策略与方法仍然是有机氟化学中的一个挑战性问题.利用过渡金属催化构筑碳-氟碳(C—Rf)键是一种有效解决上述问题的手段,但是目前该手段主要集中在利用钯或者铜催化的偶联反应来实现C—Rf键的构筑.其中钯
Fluorinated organic compounds, due to their unique properties, have important applications in such fields as medicine, pesticides and materials that are closely related to population health, national life and national defense. Although fluorine-derived organic compounds have been used in the past few years However, under the mild conditions, efficient and practical fluoridation strategies and methods are still a challenging problem in organofluorine chemistry.Using transition metal-catalyzed carbon-fluorocarbon (C-Rf) bonds Is an effective means to solve the above problems, but at present, the method mainly focuses on the use of palladium or copper-catalyzed coupling reaction to achieve C-Rf bond structure.