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近年来大量实验研究证实,胚胎神经组织植入宿主脑后,移植细胞能存活,分化,並释放神经递质或神经激素以及形成相应的突触连接以恢复一定的行为功能。哺乳动物脑移植术的成功开展,为神经系统的研究提供了一种极有价值的手段,对改善某些神经功能紊乱,纠正外伤和先天性神经疾患所致的功能缺陷,具有深远的意义。一、肽能神经元系统 (一)加压素(YP)神经元的移植正常大鼠尿渗透压可超过1600mmol/L。但Brattleboro成年大鼠,由于缺乏YP,而不能浓缩尿液,渗透压仅为300mmol
In recent years, a large number of experimental studies have confirmed that embryonic neural tissue implanted in the host brain, the transplanted cells can survive, differentiate, and release of neurotransmitters or neurohormones and the formation of the corresponding synaptic connections to restore a certain behavioral function. The successful implementation of mammalian brain transplantation provides a valuable tool for the study of the nervous system and has far-reaching significance in improving certain neurological disorders and correcting functional deficits caused by traumatic injuries and congenital neurological disorders. First, the peptide can neurons system (a) vasopressin (YP) neurons transplantation normal rat urine osmotic pressure can exceed 1600mmol / L. But Brattleboro adult rats, due to the lack of YP, can not concentrate urine, the osmotic pressure is only 300mmol