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血浆分离(Plasmapheresis,PP),做为排除血浆中毒素或有害物质在临床应用已有数年,但近几年应用范围逐渐扩大,其原因是对PP的适应证进一步了解和认识,其次是由于PP的设备改进,操作熟练以及相对安全性的提高.PP用于临床治疗疾病在国内应用尚少,作者结合文献对PP的方法和适应证做一综述.临床应用PP的目的是为排除患者血浆中免疫复合物,免疫球蛋白,异常球蛋白,以及与蛋白质结合的药物或毒素等有害物质,从而能治疗某些疾病.现用PP有两种方法,一是离心法,二是膜式法.
Plasmapheresis (PP) has been used clinically for several years to eliminate toxins or harmful substances in plasma. However, the application range has gradually expanded in recent years due to the further understanding and understanding of the indications of PP, followed by PP Of the equipment to improve, skilled operation and relative safety.PP for clinical treatment of disease in the domestic application is still small, the author combined with the literature on the PP method and indications to do a review.The purpose of clinical application of PP is to exclude the patient’s plasma Immune complexes, immunoglobulins, aberrant globulin, and protein-binding drugs or toxins and other harmful substances, which can treat some diseases. There are two ways to use PP, one is the centrifugal method, the second is the membrane method.