已有越来越多的气单胞菌被视为人类病原菌，这些细菌中存在的金属β－内酰胺酶是抗菌治疗面临的重大难题。金属β－内酚胺酶通过二价金属离子（一般为Ｚｎ２－）的转移表现其催化活性，其特点是水解底物谱广，包括碳青霉烯类抗生素在内。临床实践中对付β－内酷胺酶采取的策略? More and more Aeromonas have been identified as human pathogens, and the presence of metallo-β-lactamase in these bacteria is a major challenge for antibacterial therapy. Metal β-endo-amidase catalyzes the transfer of divalent metal ions (usually Zn2-), which is characterized by a broad spectrum of hydrolysis substrates, including carbapenem antibiotics. In clinical practice to deal with β-lactamase enzyme strategy?