脂质体作为诊断和治疗靶向药物的载体,进入体内后具有被动靶向和主动靶向2种作用,近年来,随着脂质体制备技术的进展和各种新型脂质体的出现,使其在MR靶向成像中的应用有了较快的发展,介绍了MR脂质体对比剂的特性及其制备的基本原理,总结了不同脂质体对比剂在MRI靶向成像中的应用价值。 As a carrier for diagnosis and treatment of targeted drugs, liposomes have two roles of passive targeting and active targeting after entering the body. In recent years, with the progress of liposome preparation technology and the appearance of various new liposomes, Its application in MR targeted imaging has developed rapidly, introduced the characteristics of MR liposome contrast agent and the basic principle of its preparation, and summarized the application of different liposome contrast agents in MRI targeted imaging value.