抗敏口服液研制与临床实验研究

来源 :泸州医学院学报 | 被引量 : 0次 | 上传用户:changsj
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中药抗敏口服液是以祖国传统中医药理论为立论组方依据,以酸甘止痒合剂临床应用研究取得良好效果的前期工作为基础,精选药物,科学组方,制成的纯天然抗过敏口服制剂.其制备工艺科学简便,所批质量标准能控制制剂质量.药效学实验表明:抗敏口服液具有抗刊型、I型变态反应作用和抗炎解热作用.毒理学试验研究表明:该制剂安全可靠,对大鼠心、肝、脾、肺、肾、脑等重要器官均无损害作用,对大鼠生长发育无影响。临床应用结果提示;中药抗敏口服液治疗荨麻疹、丘疹性等麻疹、过敏性鼻炎及小儿哮喘等过敏性疾病的痊愈(临床控制)率为64.9%,痊愈加显效率为86.8%。总有效率为93.2%.副作用小和无中枢镇静作用方面可与总斯敏媲美,且其复发率更低.表明抗敏口服液这一中药新型液体口服制剂具有疗效好、作用快、副作用小及治愈后复发率低等善治慢性、难治之症的特色,是一种无镇静和嗜睡到作用的纯天然抗过敏新药。 The traditional Chinese medicine anti-allergy oral liquid is based on the traditional Chinese medicine theory of the motherland and is based on the basis of the prescription. It is based on the preliminary work that has achieved good results in the clinical application research of the sour Ganzhi Anti-Itching Mixture. Allergic oral preparations. The preparation process is scientific and simple, and the approved quality standards can control the preparation quality. Pharmacodynamic experiments show that: Anti-allergy oral liquid has anti-type, type I allergic reaction and anti-inflammatory antipyretic effect. Toxicological studies have shown that the preparation is safe and reliable, has no damage to the heart, liver, spleen, lung, kidney, brain and other important organs of rats, and has no effect on the growth and development of rats. Clinical application results suggest that the recovery (clinical control) rate of allergic diseases such as urticaria, pimples, measles, allergic rhinitis and pediatric asthma was 64.9%, and the recovery rate was 86.8. %. The total effective rate is 93.2%. Side effects and no central sedation are comparable to total Sim, and their recurrence rate is lower. It shows that this new type of liquid oral preparation of traditional Chinese medicine has the advantages of good curative effect, quick action, small side effect and low recurrence rate after cure. It is a characteristic of good treatment of chronic and intractable diseases. It is a kind of natural anti-allergy oral solution that has no sedation and lethargy. Allergy medicine.
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