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目的:了解围手术期患者抗菌药物的使用情况,评价用药的合理性,为临床合理应用抗菌药物提供依据。方法:回顾性调查2007年1-6月符合遴选标准的围手术期患者412例,对临床预防性应用抗菌药物的合理性进行分析评价。结果:412例围手术期患者抗菌药物应用率为100%,涉及9大类共31个品种。经综合分析,不合理用药中Ⅰ类切口为63.93%,Ⅱ类切口为58.83%。不合理用药主要表现为术后用药时间过长、用药剂量大、选药档次过高等。结论:应严格遵守《抗菌药物临床应用指导原则》,规范围手术期抗菌药物的应用,提高抗菌药物合理应用水平。
Objective: To understand the use of antimicrobial agents in patients during perioperative period, to evaluate the rationality of drug use, and to provide the basis for clinical rational use of antimicrobial agents. Methods: A retrospective survey of 412 cases of perioperative patients meeting the selection criteria from January to June in 2007 was conducted to evaluate the rationality of preventive prophylactic antibiotics. Results: The application rate of antimicrobial agents in 412 perioperative patients was 100%, involving 31 varieties in 9 major categories. After a comprehensive analysis, irrational use of Ⅰ-type incision was 63.93%, Ⅱ-type incision was 58.83%. Irrational use of drugs mainly for the treatment of time is too long, the dosage, selection of drugs is too high grade. Conclusion: The Guidelines for Clinical Application of Antibacterial Drugs should be strictly observed to regulate the application of perioperative antibacterials and improve the rational application of antimicrobial agents.