多发性骨髓瘤(multiple myeloma,MM)又称浆细胞骨髓瘤。骨髓瘤细胞在骨髓内恶性增生,浸润骨骼或软组织,导致骨骼破坏,引起骨痛、病理性骨折、高钙血症、贫血等。血清中单克隆蛋白(monoclonal protein,M-蛋白)或其多肽链的亚单位增多,正常免疫球蛋白减少,临床上常有感染、出血及肾功能衰竭等表现。本例患者因腰背疼痛起病,查本-周蛋白阳性,进 Multiple myeloma (MM), also known as plasma cell myeloma. Myeloma cells in the bone marrow malignant hyperplasia, infiltration of bones or soft tissue, leading to bone destruction, causing bone pain, pathological fractures, hypercalcemia, anemia. Serum monoclonal protein (M-protein) or polypeptide chain subunit increased, decreased normal immunoglobulin, clinically frequent infection, bleeding and renal failure and other performance. In this case, patients with low back pain onset, check this week - week protein positive, into