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发达国家,结核性脑膜炎(TM)发病率已降低,但发展中国家仍是重要问题。尽管采用有效化疗,但发病率和死亡率仍高。链霉素治疗所者致听力丧失率高达5～15%,为避免此并发症,作者旨在评价异烟肼(INH)和利福平(RP)联合治疗 TM 的疗效。作者选自1979年1月至1985年12月确诊 TM 入院的51(女27)例患儿。年龄7个月～14岁,4岁以下者26例。按病情分为3期:1期患者有发热、厌食、间
In developed countries, the incidence of tuberculous meningitis (TM) has decreased, but developing countries remain an important issue. Despite the use of effective chemotherapy, morbidity and mortality are still high. In order to avoid this complication, the authors aim to assess the efficacy of isoniazid (INH) and rifampicin (RP) in combination with TM in the treatment of patients with streptomycin-induced hearing loss of up to 5-15%. The authors were selected from 51 (27 women) admitted to hospital between January 1979 and December 1985. Aged 7 months to 14 years old, under the age of 4 in 26 cases. According to the disease is divided into 3: 1 patients have fever, anorexia, between