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目的观察固肾安胎丸联合黄体酮和单纯使用黄体酮两种不同方法对体外受精-胚胎移植(IVF-ET)术后患者的疗效比较。方法将2015年3-8月该院生殖中心IVF-ET术后288例患者,按固肾安胎丸联合黄体酮和单纯使用黄体酮两种不同黄体支持方案分成观察组141例(固肾安胎丸+黄体酮)和对照组147例(单独使用黄体酮),比较两组种植率、临床妊娠率、早期妊娠丢失率、异位妊娠率和继续妊娠率,观察年龄因素对结局的影响。结果种植率、临床妊娠率两组间差异无统计学意义(P>0.05),但观察组较对照组有增高趋势;继续妊娠率,观察组(63.83%)明显高于对照组(42.86%),差异有统计学意义(P<0.05);早期妊娠丢失率两组间差异无统计学意义(P>0.05),观察组较对照组有降低趋势;卵泡过度刺激综合征(OHSS)发生率两组差异无统计学意义(P>0.05)。观察组患者在各年龄组临床妊娠率均高于对照组,但差异无统计学意义(P>0.05)。结论 IVF-ET术后辅助固肾安胎丸治疗可收到较好的疗效。
Objective To observe the curative effect of Gushen ANCHI pills combined with progesterone and progesterone on the efficacy of in vitro fertilization-embryo transfer (IVF-ET). Methods 288 cases of post-IVF-ET in our hospital from March to August 2015 were divided into observation group (141 cases), treated with Gushen ANCHI pill combined with progesterone and progesterone Fetal pellet + progesterone) and control group 147 cases (using progesterone alone). The implantation rate, clinical pregnancy rate, early pregnancy loss rate, ectopic pregnancy rate and continuous pregnancy rate were compared between two groups. The effect of age on the outcome was observed. Results There was no significant difference in implantation rate and clinical pregnancy rate between the two groups (P> 0.05), but the observation group had a tendency to increase compared with the control group. The rate of continuing pregnancy was significantly higher in the observation group (63.83%) than in the control group (42.86% , The difference was statistically significant (P <0.05); the rate of early pregnancy loss was no significant difference between the two groups (P> 0.05), the observation group decreased compared with the control group; the incidence of ovarian hyperstimulation syndrome (OHSS) There was no significant difference between the two groups (P> 0.05). The clinical pregnancy rate in observation group was higher than that in control group in all age groups, but the difference was not statistically significant (P> 0.05). Conclusion IVF-ET postoperative adjuvant Gushenanchu pill treatment can receive better results.