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目的分析潍坊市2001-2012年急性弛缓性麻痹(Acute Flaccid Parelysis,AFP)病例流行病学特征,评价监测系统运行情况。方法采用描述流行病学方法,分析潍坊市AFP病例流行病学特征;按照世界卫生组织(WHO)和卫生部规定的各项监测指标,评价监测系统运行情况。结果潍坊市2001-2012年共报告AFP病例314例。根据病毒学诊断标准,314例均为非脊髓灰质炎(脊灰)(Non-Polio,NP)AFP(NPAFP)病例。AFP病例报告发病率在1.52/10万~2.40/10万之间,年平均报告发病率2.09/10万。AFP发病者中以5岁以下儿童为主,占76.11%。病例中服苗史≥3剂次285例,占90.76%。合格粪便样本采集率为93.63%。从37例AFP病例粪便样本中分离到非脊灰肠道病毒(Non-Polio Enterovirus,NPEV),分离率11.78%。结论潍坊市2001-2012年AFP病例监测系统各项指标以市为单位,均达到WHO和卫生部要求。为保持无脊灰状态,应保持高水平脊灰疫苗免疫接种率,提高AFP病例监测系统质量。
Objective To analyze the epidemiological characteristics of Acute Flaccid Parelysis (AFP) in Weifang from 2001 to 2012 and evaluate the operation of the monitoring system. Methods Descriptive epidemiological methods were used to analyze the epidemiological characteristics of AFP cases in Weifang City. The monitoring system was evaluated according to the monitoring indicators stipulated by the World Health Organization (WHO) and the Ministry of Health. Results A total of 314 AFP cases were reported in Weifang from 2001 to 2012. According to the criteria of virological diagnosis, 314 cases were non-Polio (NP) AFP (NPAFP) cases. The incidence of AFP cases reported between 1.52 / 100,000 to 2.40 / 100,000, the annual average reported incidence of 2.09 / 100,000. AFP incidence of children under 5 years of age, accounting for 76.11%. In the case of service Miao history of ≥ 3 doses of 285 cases, accounting for 90.76%. The sampling rate of qualified stool samples was 93.63%. Non-Polio Enterovirus (NPEV) was isolated from stool samples of 37 cases of AFP, the isolation rate was 11.78%. Conclusion Weifang City 2001-2012 AFP case monitoring system indicators to the city as a unit, have reached the WHO and the Ministry of Health requirements. To maintain a polio-free status, a high level of polio vaccine immunization coverage should be maintained to improve the quality of AFP case monitoring systems.