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应用Ｌａｄｉｓｃｈ分离及微量分析方法，对服米非司酮、炔诺酮、三苯氧胺及正常妊娠妇女的绒毛神经节苷脂（Ｇｇ）和中性鞘糖脂（Ｎ－ＧＳＬ）进行定量分析。结果证明，正常及各服药组Ｇｇ和Ｎ－ＧＳＬ组成相同；各服药组Ｇｇ总量比正常组明显减少（Ｐ＜０．０１）。各服药组绒毛ＧＭ３、ＧＭＩ与ＧＤ３、炔诺酮及三苯氧胺组ＧＴｌｂｔｂ正常组均减少（ＰＭＯ．０１和Ｐ＜０．０５）。米非司酮及三苯氧胺组的Ｎ—ＧＳＬ总量均比正常组升高，其中米非司出组织毛ＣＤＨ、ＣＴＨ增加（Ｐ＜０．０５）；而炔诺酮组则ＰＧ升高明显（Ｐ＜０．Ｏ１）。
The chorionic gangliosides (Gg) and neutral glycosphingolipids (N-GSL) in women taking mifepristone, norethindrone, tamoxifen and normal pregnant women were quantitatively analyzed by Ladisch separation and microanalysis methods. The results showed that the normal and each medication group Gg and N-GSL composition of the same; Gg total medication group was significantly lower than the normal group (P <0.01). The GM3, GMI and GD3 villus, norethindrone and tamoxifen group GTlbtb normal group were reduced in each medication group (PMO.01 and P <0.05). The total amount of N-GSL in mifepristone and tamoxifen group was higher than that in normal group, and the CDH and CTH in hair of mifepristone group were increased (P <0.05) P <0.O1).