本文采用放射免疫分析法对40例急性缺血性中风患者脑脊液β—EP和 DynA_(1-13)含量进行了观察。结果表明,脑梗塞患者脑脊液β—EP 含量明显升高,且病情重和梗塞体积大者β—EP 升高的幅度比病情轻和病损小者大,而 DynA_(1-13)含量的变化正好相反。结果提示,β—EP 可能促进缺血性脑损伤的产生,DynA_(1-13)则有一定的保护作用。临床上测定脑脊液β—EP 和 DynA_(1-13)值的水平可估计缺血性脑损伤的严重程度。 The contents of β-EP and DynA_ (1-13) in cerebrospinal fluid of 40 patients with acute ischemic stroke were observed by radioimmunoassay. The results showed that the content of β-EP in cerebrospinal fluid of patients with cerebral infarction was significantly increased, and the increase of β-EP in severe illness and infarction volume was larger than that in mild disease and disease lesion, while the change of DynA_ (1-13) exactly the opposite. The results suggest that β-EP may promote the production of ischemic brain injury, DynA_ (1-13) has a protective effect. The level of β-EP and DynA_ (1-13) in cerebrospinal fluid can be estimated clinically to assess the severity of ischemic brain injury.