益生菌是一组寄生于人体肠道的正常菌群,通过生物拮抗改善宿主肠道菌群生态平衡、刺激肠黏膜内皮细胞分泌的分泌型免疫球蛋白而发挥免疫增强作用,从而达到提高寄生宿主健康状态的微生物[1]。益生菌具有生物夺和营养、生物拮抗、免疫增强作用,在各系统应用越来越广泛,现将国内外益生菌临床应用研究归纳如下。1益生菌常用菌株临床常用益生菌有乳酸杆菌、粪链球菌、枯草杆菌、婴儿双歧杆菌、酪酸梭菌、酵母菌、肠球菌、蜡样芽孢杆 Probiotics is a group of normal parasites in the human intestinal flora, biological antagonism to improve the host intestinal flora ecological balance, stimulate the secretion of intestinal mucosal endocrine secreted immunoglobulin and play an immune enhancement, so as to improve the parasitic host Healthy microorganisms [1]. Probiotics with biological and nutritional deprivation, bio-antagonism, immune enhancement, more widely used in various systems, the clinical application of probiotics at home and abroad are summarized as follows. A probiotic strains commonly used in clinical probiotics are Lactobacillus, Streptococcus faecalis, Bacillus subtilis, Bifidobacterium infantis, Clostridium butyricum, yeast, Enterococcus, Bacillus cereus