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目的探讨宫颈环形电刀切除术(LEEP)诊治宫颈上皮内瘤变(CIN)的价值。方法回顾性分析经阴道镜活检明确为CIN者106例行LEEP术的诊治资料。结果经阴道镜活检,病理证实CIN者106例,行LEEP术,术后病理报告:宫颈黏膜慢性炎10例(9.43%),CINⅠ44例(41.51%),CINⅡ37例(34.91%),CINⅢ10例(9.43%);原位癌累及腺体伴早期浸润癌5例(4.72%)。术后97例宫颈标本切缘阴性;病理降级29例(27.36%),等级63例(59.43%),升级14例(13.21%)。LEEP术一次治愈率达84.91%(切缘阴性)。结论 LEEP术治疗CIN安全有效,并发症少。CIN为多点病变,分级变异性较大,LEEP术还能在治疗宫颈病变的同时诊断出更高级别病变,弥补阴道镜诊断的不足。
Objective To evaluate the value of cervical ring electrotome excision (LEEP) in the diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Methods Retrospective analysis of 106 patients with CIN who underwent colposcopy biopsy for diagnosis and treatment of LEEP. Results Colposcopic biopsy showed that 106 cases of CIN were pathologically confirmed by LEEP. Postoperative pathological reports included 10 cases of chronic cervicitis (9.43%), CINⅠ44 cases (41.51%), CINⅡ37 cases (34.91%), CINⅢ10 cases 9.43%). 5 cases (4.72%) of adenocarcinoma with early invasive carcinoma were involved in carcinoma in situ. After the operation, 97 cases of cervical specimens had negative margins, 29 cases (27.36%) were pathologically degraded, 63 cases (59.43%) were escalated, and 14 cases (13.21%) were escalated. LEEP a cure rate of 84.91% (negative margin). Conclusion LEEP is safe and effective in treating CIN with few complications. CIN is a multi-point disease, grading variability larger, LEEP surgery can also treat cervical lesions at the same time diagnosing a higher level of lesions, to make up for the lack of colposcopy diagnosis.