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１９８９～１９９０年我所应用自采的河南省叶下珠（ｐｈｙｌｌａｎｔｈｕｓｎｉｒｕｎａｒｉａＬ）、海南省叶下珠（ｐｈｙｌｌａｎｔｈｕｓｎｉｒｕｒｉＬ）以及由印度Ｔｈｙａｇａｒａｊａｎ提供的叶下珠（ｐｈｙｌｌａｎｔｈｕｓａｍａｒｕｓＬ）治疗乙型肝炎患者分别为３５例、４２例及１１例。结果ｐｈｙｌｌａｎｔｈｕｓｎｉｒｕｎａｒｉａＬ组对ＨＢｅＡｇ有转阴作用，对ＨＢｅＡｂ有转阳作用，其余两种皆无这种作用。上述三种对ＨＢｓＡｇ转阴皆无作用，与文献报道ｐｈｙｌ－ｌａｎｔｈｕｓａｍａｒｕｓＬ治疗乙型肝炎患者３０天有５９％（２２／３７）的患者ＨＢｓＡｇ可转阴的结果完全不一致，而与Ｌｅｅｌａｒａｓａｍｅｅ［６］及ＲａｍｅｓｈＲａｊａｇｏｐａｌ［７］的报道一致。
From 1989 to 1990, 35 cases of hepatitis B patients were treated with phyllanthus nirunaria L, phyllanthus niruri L from Henan Province and phyllanthusamarus L from Thyagarajan India. Cases and 11 cases. Results The phyllanthus nirunaria L group had a negative effect on HBeAg and had a positive effect on HBeAb, while the other two did not. None of the above-mentioned three kinds of HBsAg negative effects had any effect. In contrast with the reported results of 59% (22/37) of patients with phyl-lanthusamarusL treatment of hepatitis B in 30 days, the results of HBsAg negative conversion were completely inconsistent, but with Leelarasamee [6] and Ramesh Rajagopal [7] reported consistent.