论文部分内容阅读
目的 :探讨基础疗法联合脐血输注对肝功能衰竭患者的治疗效果。方法 :将 4 2例急性肝功能衰竭病人分成 2组 ,脐血组2 1例以基础治疗加用脐血 12 U在 3周内进行静脉输注 ,对照组 2 1例在相同的基础治疗上加用同量成人血 3周内静脉输注 ,治疗结束后比较两组血常规和肝功能变化 ,同时观察两组临床疗效、出血及输血反应等。结果 :脐血组在提高白蛋白和血小板 ,降低凝血酶原时间和总胆红素及输血反应发生等方面与对照组比较差异有统计学意义 (均 P <0 .0 5 ) ,而两组红细胞、白细胞及出血等方面比较差异均无统计学意义 (均 P >0 .0 5 )。结论 :基础疗法联合脐血输注对急性肝功能衰竭患者肝功能的改善有较好的作用 ,并能提高血小板计数。输注脐血在肝功能衰竭的治疗上可代替成人血。
Objective: To investigate the therapeutic effect of basic therapy and umbilical cord blood transfusion on patients with liver failure. Methods: Forty-two patients with acute liver failure were divided into two groups. In the umbilical cord blood group, 21 patients received basic treatment plus 12 U of cord blood for intravenous infusion within 3 weeks, and 21 patients in the control group received the same basic treatment Plus the same amount of adult blood within 3 weeks of intravenous infusion, after treatment, compared two groups of blood and liver function changes, while observing the two groups of clinical efficacy, bleeding and transfusion reactions. Results: The umbilical cord blood group had significant difference compared with the control group in increasing albumin and platelet count, reducing prothrombin time, total bilirubin and transfusion reaction (all P <0.05), while two groups There were no significant differences in erythrocytes, white blood cells and hemorrhage (all P> 0.05). Conclusion: The combination of basic therapy and umbilical cord blood transfusion has a good effect on the improvement of liver function in patients with acute liver failure, and can improve the platelet count. Infusion of cord blood in the treatment of liver failure can replace adult blood.