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我科自1990年以低右并肝素治疗胆汁淤积性肝炎22例,并以门冬氨酸钾镁及强力宁治疗18例作对照。诊断标准:临床有明显黄疸、皮肤搔痒,血清总胆红素(SB)及直接胆红素升高,AKPr—GT,ALT升高,黄疸持续6至8周。治疗方法:治疗组低右500ml+肝素50mg,静满1次/d。对照组用10%葡萄糖500ml分别加门冬氨酸钾镁60ml、强力宁80ml静滴1次/d。疗效观察:用药两周后SB及ALT下降≥50%为有效,否则为无效。观察SB治疗组有效20例,无效2例,对照组有效5例,无效13例。观察ALT治疗组有效19例,无效
Our department since 1990 with low right and heparin in the treatment of cholestatic hepatitis in 22 cases, and aspartate magnesium potassium and strong Ning treatment of 18 cases as a control. Diagnostic criteria: clinically obvious jaundice, itchy skin, serum total bilirubin (SB) and direct bilirubin, AKPr-GT, ALT increased, jaundice for 6 to 8 weeks. Treatment: lower right treatment group 500ml + heparin 50mg, calm full 1 / d. Control group with 500ml of 10% glucose plus potassium aspartate 60ml, strong Ning 80ml intravenous infusion 1 / d. Efficacy of treatment: two weeks after treatment SB and ALT decreased ≥ 50% is valid, otherwise invalid. Observed SB treatment group effective in 20 cases, 2 cases invalid, control group effective in 5 cases, ineffective in 13 cases. Observation of ALT treatment group effective in 19 cases, invalid