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目的了解血清心肌酶及同工酶的检测在小儿腹泻病中的应用价值。方法收集在本院住院或门诊治疗的136例小儿腹泻患者按照不同的病因分为3组,其中轮状病毒感染组(A组)48例,杯状病毒感染组(B组)42例,其他病因即无病毒感染组(C组)46例,分别检测各组血清心肌酶及同工酶,分析结果的相关性。结果在3组结果中,轮状病毒感染组(A组)和杯状病毒感染组(B组)心肌酶及同工酶均有不同程度的升高,A组和B组心肌酶及同工酶各项指标即CK、CK-MB、AST、LDH检测结果分别与正常对照组(C组)的检测结果比较,均具有非常显著性差异,t值分别为20.5465、18.1795、10.9286、20.6550;19.1351、16.3385、6.6103、18.2089,(P均<0.01)。而A组和B组比较,差异无统计学意义,t分别为0.6169、1.4914、1.6457、0.3571,(P均>0.05)。结论轮状病毒和人类杯状病毒感染引起的婴幼儿腹泻,可引发不同程度的心肌损害,两种病毒对心肌损伤的程度无明显的差异,提示血清心肌酶及同工酶的检测可间接为小儿腹泻临床诊断提供有力的依据。
Objective To understand the value of serum myocardial enzymes and isoenzymes detection in children with diarrhea. Methods A total of 136 pediatric patients with diarrhea admitted to our hospital were enrolled in this study. The patients were divided into 3 groups according to different etiology. Among them, 48 cases were infected with rotavirus (A group), 42 cases were infected with calicivirus (Group B) The cause of the virus-free infection group (C group) 46 cases were detected in each group of serum myocardial enzymes and isoenzymes, analysis of the correlation. Results In the three groups of patients, the levels of myocardial enzymes and isoenzymes in rotavirus group (group A) and group B (group B) were increased to some extent. The levels of myocardial enzymes and co-workers in groups A and B The indexes of CK, CK-MB, AST and LDH were significantly different from those of normal control group (C group), the values of t were 20.5465,18.1795,10.9286,20.6550 respectively; 19.1351 , 16.3385,6.6103,18.2089, respectively (all P <0.01). There was no significant difference between group A and group B (t = 0.6169,1.4914,1.6457,0.357 1, P> 0.05). Conclusions Infantile diarrhea caused by rotavirus and human calicivirus can cause different degrees of myocardial damage. There is no significant difference between the two viruses in the degree of myocardial injury, suggesting that the detection of serum myocardial enzymes and isozymes may indirectly Clinical diagnosis of pediatric diarrhea provide a strong basis.