论文部分内容阅读
[目的]了解输血传播病毒(TTV)在新疆结核病患者中的感染情况。[方法]采用套式PCR方法检测229例结核病患者及180例一般人群血清进行TTV-DNA检测,并分析TTV-DNA阳性者的临床特点。[结果]在229例结核患者中共检出51例TTV-DNA阳性血清,总检出率为22.3%,其中老年结核患者组TTV-DNA阳性率为36.8%(21/57),中年结核患者为18%,青少年结核患者组为15.9%,老年结核患者组TTV-DNA阳性率明显高于中年结核患者组和青少年结核患者组,差异有统计学意义(P﹤0.05)。维吾尔族与汉族相比,以及男性与女性相比均无统计学差异(P﹥0.05)。[结论]新疆结核病患者中存在较高的TTV感染,老年结核病患者更加容易感染TTV。
[Objective] To understand the infection of transfusion transmitted virus (TTV) in Xinjiang tuberculosis patients. [Method] The nested PCR method was used to detect the serum of 229 tuberculosis patients and 180 normal people for TTV-DNA test and to analyze the clinical features of TTV-DNA positive patients. [Results] A total of 51 TTV-DNA positive sera were detected in 229 tuberculosis patients, with a total positive rate of 22.3%. Among them, the positive rate of TTV-DNA in elderly TB patients was 36.8% (21/57). Middle-aged tuberculosis patients (18%) and 15.9% (TB) patients. The positive rate of TTV-DNA in elderly TB patients was significantly higher than that in middle-aged TB patients and adolescent tuberculosis patients (P <0.05). Uygur and Han nationality compared to men and women were no significant difference (P> 0.05). [Conclusion] There is a high TTV infection in tuberculosis patients in Xinjiang, and the elderly patients with tuberculosis are more likely to be infected with TTV.