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目的:探讨超短回波时间（UTE）-Tn 2*成分分析技术在参加马拉松赛的业余马拉松运动员跟腱形态及生化变化动态监测中的价值。n 方法:招募2020年10月至2021年3月广东省珠海市业余马拉松运动员29名，其中男25名，女4名，年龄24~50（40±6）岁。所有运动员于马拉松赛前1周、赛后48 h内及赛后1个月分别接受双侧跟腱MRI检查，采用常规Tn 1加权像、质子密度加权压脂序列和不同回波时间（TE）的UTE序列对跟腱的形态及信号进行评估，采用UTE-Tn 2*序列对跑步后跟腱生化的改变进行动态定量分析。UTE-Tn 2*序列获得单成分分析值（Tn 2*n M）和双成分分析的短Tn 2*成分值（Tn 2*n S）和长Tn 2*成分值（Tn 2*n L）以及百分比值。在跟腱矢状位图像上测量跟腱整体的数值，并把跟腱等分为3个亚区分别测量（跟腱连接段、跟腱中间段、跟腱插入段），由2名放射科医师独立勾画感兴趣区。用组内相关系数（ICC）法对2名放射科医生的定量结果进行一致性检验；采用非参数的Friedman n M检验比较不同时间点、不同亚区Tn 2*n M、Tn 2*n S、Tn 2*n L和百分比值的差异；使用Wilcoxon秩和检验比较不同距离、不同跑姿、不同配速及不同训练量的赛后48 h与赛前Tn 2*n S的变化差异（ΔTn 2*n S），其中ΔTn 2*n S为赛后48 h Tn 2*n S值与赛前Tn 2*n S值的差值。n 结果:在短TE（TE≤0.6 ms）的序列上，跟腱腱病可表现为高信号区域出现散在点状低信号。2名放射科医师对跟腱的Tn 2*n M、Tn 2*n S、Tn 2*n L和百分比值测量的一致性好，ICC值分别为0.96、0.94、0.83和0.94。跟腱的整体、跟腱连接段及跟腱中间段的Tn 2*n S值在马拉松运动后48 h均轻度升高，运动1个月后减低［0.49（0.45，0.59）比0.54（0.49，0.59）比0.53（0.49，0.57），0.48（0.44，0.54）比0.53（0.47，0.58）比0.50（0.46，0.57），0.48（0.43，0.58）比0.54（0.47，0.59）比0.52（0.46，0.57）；均n P0.05）。不同的跑姿中，前中脚掌着地者跟腱整体ΔTn 2*n S高于后脚掌着地者［0.03（-0.05，0.07）比-0.03（-0.17，0.11），n P = 0.001］。n 结论:UTE-Tn 2*的双成分分析技术对运动前后的跟腱形态动态变化监测优于单成分分析，其Tn 2*n S对跟腱内化学成分的细微变化更加敏感。n “,”Objective:To explore the value of ultra-short echo time (UTE)-Tn 2* component analysis techniques in dynamic monitoring the morphological and biochemical changes in amateur marathon athletes′ achilles tendon before and after the marathon.n Methods:Twenty-nine amateur marathon runners were recruited between October 2020 and March 2021 in Zhuhai City, Guangdong Province, including 25 males and 4 females, aged from 24 to 50 (40±6) years old. All volunteers underwent bilateral achilles tendon MRI examination 1 week before the marathon, 48 hours after the race, and 1 month after the race. The shape and signal of the achilles tendon were evaluated by routine T1-weighted, proton density weighted with fat saturation sequence and different echo time (TE) UTE sequence, and the changes of achilles tendon after running was quantitatively analyzed by UTE-T2* sequence. The values of single-component analysis (Tn 2*n M), short Tn 2* components (Tn 2*n S), and long Tn 2* components (Tn 2*n L) and Fraction values were obtained using UTE-Tn 2* sequence. The value of the whole achilles tendon was measured on the sagittal images of achilles tendon, and the Achilles tendon was equally divided into three subregions [muscle-tendon junction (MTJ), middle (MID), and insertion (INS)]. The region of interest was delineated by two radiologists independently. The intra-group correlation coefficient (ICC) was used to evaluate the consistency of the data measured by two radiologists. Nonparametric Friedman n M test was used to compare the differences of Tn 2*n M, Tn 2*n S, Tn 2*n L and Fraction values in different time points and different subregions. Wilcoxon rank-sum test was used to compare the difference between 48 h post-race and pre-race Tn 2*n S values (ΔTn 2*n S) of different distance, different running posture, different pace and different amount of training, in which ΔTn 2*n S equals the Tn 2*n S value of 48 h post-race minus the Tn 2*n S value of pre-race.n Results:On the sequence of short TE (TE≤0.6 ms), achilles tendinopathy can manifest as scattered punctate hypointensity in areas of high signal intensity. The two radiologists showed a good consistency in measuring the Tn 2*n M, Tn 2*n S, Tn 2*n L and Fraction values of the achilles tendon, and the ICC values ??were 0.96, 0.94, 0.83 and 0.94, respectively. The Tn 2*s values was significantly higher in the whole Achilles tendon, MTJ and MID segment at 48 h post-exercise compared to pre-exercise, and decreased after 1 month of exercise, [0.49 (0.45, 0.59) vs 0.54 (0.49, 0.59) vs 0.53 (0.49, 0.57), 0.48 (0.44, 0.54) vs 0.53 (0.47, 0.58) vs 0.50 (0.46, 0.57), 0.48 (0.43, 0.58) vs 0.54 (0.47, 0.59) vs 0.52 (0.46, 0.57); respectively, all n P0.05). In different running gestures, the ΔTn 2*n S of achilles tendon who using the postures of front-middle feet is higher than that using the postures of back feet (0.03(-0.05, 0.07) vs -0.03(-0.17, 0.11), n P=0.001).n Conclusion:The Bi-component analysis of UTE-Tn 2* technology is superior to single component analysis in monitoring the dynamic changes of achilles tendon before and after exercise, and Tn 2*n S is a more sensitive sequence to evaluate the subtle changes in the chemical composition of achilles tendon.n