论文部分内容阅读
β-内啡肽(β-EP)是近年发现的与脑缺血性损伤病理生理过程密切相关的神经肽。本文报道35例缺血性脑卒中患者血浆及脑脊液中β-EP含量测定,并初步探讨了其临床意义。 1 材料与方法 1.1 检测对象:病例组:均系近3年来随机选择的住院病人,年龄43～82岁,平均年龄54岁,其中脑梗塞29例,混合型中风6例,全部病例均经CT或磁共振明确诊断。所有对象取样前均未使用糖皮质激素。对照组:健康体检者30例,年龄27～60岁,平均46岁。 1.2 方法:在病人急性发病期间同时抽取肘静脉血、脑脊液。静脉血用EDTA—Na_2抗凝(每管内
Beta-endorphin (β-EP) is a neuropeptide that has been found to be closely related to the pathophysiological process of cerebral ischemic injury in recent years. This article reports the determination of β-EP in plasma and cerebrospinal fluid in 35 patients with ischemic stroke and preliminarily discusses its clinical significance. 1 Materials and Methods 1.1 Test Object: Case Group: All patients were randomly selected in the past 3 years, aged 43 to 82 years, mean age 54 years, of which 29 cases of cerebral infarction, mixed stroke in 6 cases, all cases were CT Or a clear diagnosis of magnetic resonance. All subjects did not use glucocorticoids before sampling. Control group: 30 healthy subjects, aged 27 to 60 years, mean 46 years old. 1.2 Methods: In the acute onset of patients while extracting elbow venous blood, cerebrospinal fluid. Venous blood was anticoagulated with EDTA-Na 2 (within each tube