论文部分内容阅读
观察了消炎痛在豚鼠胆色素结石形成过程中的作用。实验动物随机分为三组：对照组C，胆总管狭窄组［s］和胆总管狭窄＋消炎痛组［s＋I。实验结果与［c］和［s＋I］组相比，［s］组胆汁中的Ca2、Na、总蛋白和胆红素显著增高，K浓度减低（P＜0．05～P＜0·01）。胆固醇浓度元差异。［s］组的胆囊成石率显著高于［c］和［S＋I］组（P＜0．01）。胆汁SDS-PAGE显示［S］组蛋白电泳谱带多于［C］和［S＋I］组。这两组无统计学差异。提示消炎痛可以延缓胆囊胆色素结石的形成并有可能用于治疗胆囊结石。
The role of indomethacin in the formation of porcine pigmented stones was observed. The experimental animals were randomly divided into three groups: control group C, common bile duct stenosis group [s] and common bile duct stenosis + indomethacin group [s + I. Experimental results Ca2 +, Na +, total protein and bilirubin in [s] group were significantly increased and K concentration was decreased (P <0.05 ~ P <0.01) compared with [c] and [ . Cholesterol concentration yuan difference. The rate of gallstone formation in [s] group was significantly higher than that in [c] and [S + I] groups (P <0.01). Bile SDS-PAGE showed that the [S] histone electrophoresis bands were more than [C] and [S + I] groups. There was no statistical difference between the two groups. Indomethacin may delay the formation of gallstone and may be used to treat gallstones.