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目的定量分析肝脏病灶的超声造影(CEUS)参数和声触诊组织量化技术(VTQ)成像特征,对比二者诊断良恶性病灶中的应用价值。方法对79枚肝脏病灶分别进行CEUS和VTQ检查。CEUS动态图像采用QLAB定量软件对病灶绘制时间-强度曲线(TIC),并获取相关的声学定量参数,VTQ检查获得病灶及周围背景肝组织剪切波速度(SWV),比较两种方法在肝脏病灶中的诊断价值。结果肝脏恶性病灶的SWV值明显高于良性病灶,差异具有统计学意义(P<0.01);VTQ和CEUS诊断肝脏良恶性病灶的ROC曲线下面积分别为0.811和0.984,差异具有统计学意义(P<0.05);VTQ对于CEUS诊断不确切的病灶诊断准确度66.67%。结论 CEUS和VTQ在肝良恶性病灶的鉴别诊断中均有较高应用价值,且CEUS诊断价值更高一些,但对于其无法定性的病灶,VTQ有一定的补充诊断价值。
Objective To quantitatively analyze the features of CEUS and VTQ in liver lesions and compare the diagnostic value between the two methods in the diagnosis of benign and malignant lesions. Methods 79 liver lesions were examined by CEUS and VTQ respectively. CEUS dynamic images using QLAB quantitative software to plot the time-intensity curve (TIC) of the lesion, and obtain the relevant acoustic quantitative parameters, VTQ examination of the lesion and peripheral background liver tissue shear wave velocity (SWV), compare the two methods in the liver lesions In the diagnostic value. Results The SWV of malignant liver lesions was significantly higher than that of benign lesions (P <0.01). The area under the ROC curve of VTQ and CEUS in diagnosing benign and malignant liver lesions were 0.811 and 0.984, respectively, and the difference was statistically significant (P <0.05). The diagnostic accuracy of VTQ for the lesions with inaccurate CEUS diagnosis was 66.67%. Conclusion CEUS and VTQ are of high value in the differential diagnosis of benign and malignant liver lesions, and CEUS has higher diagnostic value. However, VTQ can be used as a supplementary diagnostic value for those lesions that can not be identified.