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应用聚合酶链反应(PCR)技术对Y染色体特异DNA序列进行体外扩增,结果表明可用体外PCR扩增方法检查胎儿绒毛或羊水确定胎儿性别。这种方法快速、准确、简便,对X连锁遗传病的产前诊断具有重要意义。
The Y chromosome specific DNA sequence was amplified by polymerase chain reaction (PCR) in vitro. The results showed that fetus villus or amniotic fluid could be examined by in vitro PCR amplification to determine the sex of the fetus. This method is rapid, accurate and simple, and is of great significance to the prenatal diagnosis of X-linked genetic diseases.