1874年首先由Leyden 描述肌强直营养不良症为先天性肌强直症,又称萎缩性肌强直症,是一种罕见的常染色体显性遗传性疾病。起病隐避,病情进行缓慢,多在20～30岁发病,多在45岁以前死于并发病。患者吕××男36岁工人住院号51139 右眼视物不清2年,诊断为白内障。于1981年3月20日入院。从20岁开始智力逐渐低下,口齿不清,行走苯拙。两年前,无明显诱因而视力进行性下降。近半年仅能辨别光亮。父母非近亲联婚,家族中无同样疾病。患者25岁结婚,因不育离婚,5年前再 1874 First described by Leyden Myotonic dystrophy is congenital myotonia, also known as atrophic myotonia, is a rare autosomal dominant genetic disease. Stealth onset, the condition is slow, mostly in the 20 to 30-year-old onset, and more died before the age of 45 and concurrent disease. Patient LV × × male 36-year-old worker hospital number 51139 The right eye blurred vision 2 years, diagnosed as cataracts. March 20, 1981 admission. From the age of 20 began to gradually lower intelligence, slurred speech, walking benzene clumsy. Two years ago, there was no obvious incentive for a progressive loss of vision. Nearly six months can only distinguish between bright. Parents of non-relatives of marriage, the same family of no disease. Patient 25 years old married, divorced because of infertility, and then 5 years ago