论文部分内容阅读
为了解脑梗塞患者体内是否仍存在高凝状态，通过酶联免疫、放射免疫和免疫火箭电泳的方法，采用与凝血、纤溶相关的７项分子标记物测定５３例脑梗塞患者血浆中的含量。结果，ＶＷＦ∶Ａｇ、ＴＸＢ２、ＧＭＰ—１４０、Ｄ－ｄｍ和ＰＡＩ∶Ａ指标明显高于对照组，而６－Ｋ－ＰＧＦ１α和ｔ－ＰＡ∶Ａ也明显低于对照组，各值均有非常显著性差异（Ｐ＜０．０１）。提示脑梗塞患者体内存在着血管内皮损伤、血小板激活、纤溶和抗凝激活现象，仍处在凝血功能亢进的高凝状态，如忽视抗凝治疗，有再度梗塞的可能。
In order to understand whether there is still hypercoagulable state in the patients with cerebral infarction, the content of plasma of 53 patients with cerebral infarction was determined by enzyme-linked immunosorbent assay, radioimmunoassay and immune rocket electrophoresis, using seven molecular markers related to coagulation and fibrinolysis . Results, VWF: Ag, TXB2, GMP-140, D-dm and PAI: A index was significantly higher than the control group, and 6-K-PGF1α and t-PA: A was significantly lower than the control group, Significant difference (P <0.01). Tip of patients with cerebral infarction in vivo vascular endothelial injury, platelet activation, fibrinolysis and anticoagulant activation phenomenon, is still in hypercoagulable hypercoagulable state, such as neglect of anticoagulant therapy, the possibility of re-infarction.