蛋白酶及其抑制剂的生理过程已逐步被阐明了,因此阐明两者相互作用的机制的重要性大增。另一方面艾滋病治疗是当今的重要课题,如何创制艾滋病病毒所具有的羧肽酶的酶抑制剂在加紧摸索中。从陆栖生物中至今已获得了巨大数量蛋白质(肽)性质的蛋白酶抑制剂,虽然作为蛋白质它们在构造上有相同性,但按照其基本结构仍能分为8个种类。从海洋微生物来源的蛋白质性的蛋白酶抑制剂至今才只有marinostatin,与来自 The physiological processes of proteases and their inhibitors have been gradually elucidated, and therefore the importance of elucidating the mechanisms by which the two interact. On the other hand, AIDS treatment is an important issue nowadays. How to create enzyme inhibitors of carboxypeptidases possessed by the AIDS virus is being intensified. Protease inhibitors, which have so far acquired a large number of protein (peptide) properties from terrestrial organisms, although they are structurally identical as proteins, are still classified according to their basic structure into eight classes. Only protein protease inhibitors from marine microorganisms have so far only been marinostatin,