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应用免疫组化方法，采用抗细胞角蛋白（ＣＫ）、绒毛膜促性腺激素（ｈＣＧ）、胎盘泌乳素（ｈＰＬ）抗体，检测了９１例恶性滋养细胞肿瘤不同类型滋养细胞的分布情况。结果显示，侵袭性葡萄胎和绒毛膜癌的滋养细胞组成不同。二者除了均具有较多合体滋养细胞（ＳＴ）外，前者中间型滋养细胞（ＩＴ）数量较后者明显增多，而后者细胞滋养细胞（ＣＴ）则较前者明显增多。转移性侵袭性葡萄胎与原发瘤在滋养细胞组成上无显著差异，但转移性绒毛膜癌ＳＴ较原发瘤明显增多，ＣＴ较原发瘤显著减少，ＩＴ数量虽有一定增加，但与原发瘤无显著差异。作者认为，合体滋养细胞在恶性滋养细胞肿瘤中的作用尚须进一步探讨。
Immunohistochemistry was used to detect the distribution of different types of trophoblastic cells in 91 cases of malignant trophoblastic tumor using anti-cytokeratin (CK), human chorionic gonadotropin (hCG) and placental prolactin (hPL) antibody. The results show that invasive mole and choriocarcinoma of the trophoblastic composition. In addition to having more syncytiotrophoblasts (STs), both the number of intermediate trophoblast cells (IT) increased significantly compared with the latter, while the number of cytotrophoblast cells (CT) increased significantly in the former. There was no significant difference in the composition of trophoblastic cells between metastatic hydatidiform mole and primary tumor, but metastatic choriocarcinoma ST was significantly higher than primary tumor, CT was significantly lower than primary tumor, although the number of IT increased a little, Primary tumor no significant difference. The authors believe that the role of syncytiotrophoblastic cells in malignant trophoblastic tumors needs further study.