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对１６例甲状腺癌患者进行９９ｍＴｃ-甲氧基异了基异腈（ＭＩＢＩ）显像，以探讨其对甲状腺癌的诊断价值．方法：静脉注射９９ｍＴｃ-ＭＩＢＩ３７０ＭＢｑ后５～１５分钟和１～１．５小时分别采集早、晚期前位图像各１帧．计算早、晚期摄取比值（ＵＲ）和储留指数（ＲＩ）．结果：１６个甲状腺癌原发灶中１５个有放射性填充，而３１个甲状腺良性原发灶仅７个有放射性填充；７例有甲状腺癌淋巴结转移者显像均呈阳性．以晚期ＵＲ＞０．８０作为诊断甲状腺癌的下限值，诊断灵敏度、特异性和准确性分别为８７．５％、９３．５％和９１．５％，而肉眼观察仅分别为７１．４％、７７．４％和７５．６％．结论：甲状腺９９ｍＴｃ-ＭＩＢＩＥ显像对诊断甲状腺癌有临床意义，晚期ＵＲ值有助于提高诊断的灵敏度．
16 cases of thyroid cancer patients underwent 99mTc-methoxy-isopentenylisonitrile (MIBI) imaging to explore its diagnostic value of thyroid cancer. Methods: The early and late anterior images were collected at 5 to 15 minutes and 1 to 1.5 hours after intravenous injection of 99mTc-MIBI370MBq. Calculate the early and late uptake ratio (UR) and retention index (RI). Results: Fifteen of the 16 primary thyroid carcinomas had radioactive filling, while only 7 of 31 primary thyroid benign tumors had radioactive filling. Seven patients with lymph node metastasis of thyroid carcinoma showed positive imaging. The diagnostic sensitivity, specificity and accuracy of diagnosis of thyroid cancer were 87.5%, 93.5% and 91.5%, respectively, with UR> 0.80 as the lower limit of diagnosis %, 77.4% and 75.6%. Conclusions: Thyroid 99mTc-MIBIE imaging is of clinical significance in the diagnosis of thyroid cancer. The value of late UR is helpful to improve the diagnostic sensitivity.